Search | Engineering

Subscribe Submit

Home Journals Focus Achievement Fronts About Us 中文版

Resource Type

Journal Article 468

Year

2024 2

2023 48

2022 55

2021 49

2020 49

2019 39

2018 41

2017 34

2016 32

2015 37

2014 31

2013 8

2012 12

2011 3

2010 4

2009 3

2008 4

2007 2

2005 2

2004 2

open ︾

Keywords

Chlorella sp. HQ 3

Escherichia coli 3

NO_x 3

Akkermansia muciniphila 2

Botrytis cinerea 2

C. dubia 2

E. coli 2

Eucalyptus 2

Hevea brasiliensis 2

J-integral 2

Manihot esculenta 2

Microcystis aeruginosa 2

N 2

N-nitrosodimethylamine 2

Neospora caninum 2

Pseudomonas 2

Puccinia striiformis f. sp. tritici 2

Triticum aestivum 2

β-glucuronidase 2

open ︾

Search scope:

排序： Display mode:

Catalytic oxidation of

Na Li, Xin Xing, Yonggang Sun, Jie Cheng, Gang Wang, Zhongshen Zhang, Zhengping Hao

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 6, doi: 10.1007/s11783-020-1284-3

Abstract: Abstract • Superior catalytic activity observed for o-chlorophenol oxidation on Co2MgAlO. • The reducibilityoxygen species and basicity influenced catalytic activity. • The organic by-products were generated in o-chlorophenolmetal oxides (Co2XAlO, X= Co, Mg, Ca and Ni) were investigated for the deep catalytic oxidation of o-chlorophenolThe Co2MgAlO catalyst presented the best catalytic activity, and could maintain 90% o-chlorophenol conversionThe organic by-products generated during the o-chlorophenol catalytic oxidation over Co2MgAlO catalyst

Keywords： Hydrotalcite-derived mixed oxides oi>-chlorophenol Catalytic oxidation Organic by-products

HTML PDF Collect

Enhanced 4-chlorophenol biodegradation by integrating FeO nanoparticles into an anaerobic reactor: Long-term

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1519-6

Abstract:

• 4-chlorophenol biodegradation could be enhanced in Fe₂O

Keywords： Dechlorination Fe₂O₃ nanoparticles Electron transfer Microbial community

HTML PDF Collect

The impact of hypoxia in hepatocellular carcinoma metastasis

Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Irene Oi-Lin Ng

Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 33-41 doi: 10.1007/s11684-013-0301-3

Abstract:

Hypoxia is a common phenomenon in hepatocellular carcinoma (HCC). Hypoxia stabilizes transcription factor, hypoxia-inducible factor (HIF), to activate gene transcription. Expression of HIF is closely associated with metastasis and poor prognosis in HCC. HIF mediates expression of genes that are involved in every step of HCC metastasis including epithelial-mesenchymal transition, invasion of the extracellular matrix, intravasation, extravasation, and secondar y growth of the metastases. Because HIF is the central regulator of HCC metastasis, HIF inhibitors are attractive tools when used alone or as combined treatment to curb HCC metastasis. This review will summarize the current findings on the impact of hypoxia/HIF in HCC, with a particular focus on cancer metastasis.

Keywords： hypoxia hepatocellular carcinoma (HCC) metastasis hypoxia-inducible factor (HIF)

HTML PDF Collect

Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

Sandy Leung-Kuen Au, Irene Oi-Lin Ng, Chun-Ming Wong

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 231-241 doi: 10.1007/s11684-013-0253-7

Abstract:

Hepatocellular carcinoma (HCC) development is characterized by the presence of epigenetic alterations, including promoter DNA hypermethylation and post-translational modifications of histone, which profoundly affect expression of a wide repertoire of genes critical for cancer development. Emerging data suggest that deregulation of polycomb group (PcG) proteins, which are key chromatin modifiers repressing gene transcription during developmental stage, plays a causative role in oncogenesis. PcG proteins assemble into polycomb repressive complex 1 (PRC1) and polycomb repressive complex 2 (PRC2) to impose the histone H3 lysine 27 trimethylation (H3K27me3) modification for repression. In this review, we will first recapitulate the mechanisms of two key epigenetic pathways: DNA methylation and histone modifications. Specifically, we will focus our discussion on the molecular roles of PcG proteins. Next, we will highlight recent findings on PcG proteins, their clinicopathological implication and their downstream molecular consequence in hepatocarcinogenesis. Last but not least, we will consider the therapeutic potential of targeting enhancer of zeste homolog 2 (EZH2) as a possible treatment for HCC. Improving our understanding on the roles of PcG proteins in hepatocarcinogenesis can benefit the development of epigenetic-based therapy.

Keywords： liver cancer epigenetics histone modifications polycomb group proteins enhancer of zeste homolog 2 (EZH2)

HTML PDF Collect

TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways in hepatocellular carcinoma

Daniel Wai-Hung Ho,Alan Ka-Lun Kai,Irene Oi-Lin Ng

Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 322-330 doi: 10.1007/s11684-015-0408-9

Abstract: Top-listing upregulated (CENPFi> and FOXM1i>) and downregulated (CLEC4Gi>, CRHBPi>, and CLEC1Bi>) genes were successfully validated using qPCR on our cohort of

Keywords： TCGA whole-transcriptome sequencing HCC liver cancer

HTML PDF Collect

Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 4, Pages 448-455 doi: 10.1007/s11709-014-0262-x

Abstract: Rock mass classification system is very suitable for various engineering design and stability analysis. classification method is confirmed by Japan Highway Public Corporation that this method can figure out either strength or deformability of rock mass, further appropriating the amount of rock bolts, thickness of shotcrete, and size of pitch of steel ribs just after the blasting procedure. Based on these advantages of method, in this study, according to data of five deep and long tunnels in Iran, two equations for estimating the value of method from and classification systems were developed. These equations as a new method were able to optimize the support system for and classification systems. From classification and its application in these case studies, it is pointed out that the method for the design of support systems in underground working is more reliable than the and classification systems.

Keywords： JHi> classification Qi> and RMRi> classification new method

HTML PDF Collect

The Potential Role of Powdery Mildew-Resistance Gene Pm40i> in Chinese Wheat-Breeding Programs inthe Post-Pm21i> Era Perspective

Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo

Engineering 2018, Volume 4, Issue 4, Pages 500-506 doi: 10.1016/j.eng.2018.06.004

Abstract:

Powdery mildew, which is caused by Blumeria graminis f. sp. tritici (Bgt), is an important leaf disease that affects wheat yield. Powdery mildew-resistance (Pm) gene Pm21 was first transferred into wheat in the 1980s, by translocating the Heuchera villosa chromosome arm 6VS to the wheat chromosome arm 6AL (6VS·6AL). Recently, new Bgt isolates that are virulent to Pm21 have been identified in some wheat fields, indicating that wheat breeders should be aware of the risk of deploying Pm21, although pathological details regarding these virulent isolates still remain to be discovered. Pm40 was identified and mapped on the wheat chromosome arm 7BS from several wheat lines developed from the progenies of a wild cross between wheat and Thinopyrum intermedium. Pm40 offers a broad spectrum of resistance to Bgt, which suggests that it is likely to provide potentially durable resistance. Cytological methods did not detect any large alien chromosomal segment in the wheat lines carrying Pm40. Lines with Pm40 and promising agronomical traits have been released by several wheat-breeding programs in the past several years. Therefore, we believe that Pm40 will play a role in powdery mildew-resistance wheat breeding after Pm21 resistance is overcome by Bgt isolates. In addition, both Pm21 and Pm40 were derived from alien species, suggesting that the resistance genes derived from alien species are potentially more durable or effective than those identified from wheat.

Keywords： Wheat Powdery mildew Pm21i> Pm40i> Alien species Native resistance

HTML PDF Collect

NiFeRuO_xi> nanosheets on Ni foam as an electrocatalyst for efficient

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11, Pages 1698-1706 doi: 10.1007/s11705-023-2334-8

Abstract: The electrocatalyst NiFeRuO_xi>/NF, comprised of NiFeRuO_xi> nanosheetsNiFeRuO_xi>/NF displays high electrocatalytic activity and stability for overall alkalineA solar-driven system containing such a bifunctional NiFeRuO_xi>/NF has an almost 100%The NiFeRuO_xi> coating around Ni foam is an anti-corrosion layer and also a critical

Keywords： NiFeRuO_xi> nanosheets Ni foam electrocatalysis overall seawater splitting solar-driven

HTML PDF Collect

Presence and Antimicrobial Susceptibility of RE-cmeABCi>-Positive Campylobacteri> Isolated Article

Dejun Liu, Weiwen Liu, Xing Li, Hong Yao, Zhangqi Shen, Yang Wang, Jianzhong Shen

Engineering 2020, Volume 6, Issue 1, Pages 34-39 doi: 10.1016/j.eng.2019.10.013

Abstract:

Campylobacter spp. (C. spp.) are the leading cause of human gastroenteritis worldwide. RE-CmeABC is a newly identified resistance-enhancing multidrug efflux pump of C. spp. that confers high-level resistance to fluoroquinolones, phenicols, macrolides, and tetracyclines, all of which are critical drugs in both human and veterinary medicine. In this study, we analyzed the presence and antimicrobial susceptibility of RE-cmeABC-positive Campylobacter isolates of food-animal origin from three representative regions (Shandong, Shanghai, and Guangdong) in China over three successive years, from 2014 to 2016. A total of 1088 Campylobacter isolates (931 C. coli and 157 C. jejuni) were recovered from the RE-cmeABC screening. We detected 122 (11.2%) RE-cmeABC-positive isolates of chicken origin, including 111 (70.7%) C. jejuni and 11 (1.2%) C. coli. This multidrug efflux pump is more prevalent among C. jejuni than C. coli. The level of resistance was significantly different in 111 RE-cmeABC-positive C. jejuni versus 46 RE-cmeABC-negative C. jejuni for florfenicol, clindamycin, and erythromycin (P < 0.05), but not for ciprofloxacin (CIP), tetracycline (TET), and gentamicin. However, the isolates harboring RE-cmeABC could shift the minimum inhibitory concentration distribution to the higher range for CIP and TET. Pulsed-field gel electrophoresis (PFGE) analysis suggested that horizontal transmission might be involved in the dissemination of RE-cmeABC in Shanghai and Guangdong, while clonal expansion was predominant in Shandong. Three isolates shared the indiscriminate PFGE types of RE-cmeABC-positive C. jejuni isolates in Shanghai and Guangdong, and four isolates in Shanghai and Shandong. Our study suggests the possibility of a wide dissemination of RE-cmeABC in Campylobacter of food-animal origin, which would pose a significant threat to public health.

Keywords： RE-cmeABCi> Campylobacteri> Ciprofloxacin Florfenicol

HTML PDF Collect

A highly efficient methodology for the preparation of

Yongxin Zhang, Shucheng Wang, Yaodong Huang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3, Pages 679-686 doi: 10.1007/s11705-020-1979-9

Abstract: A convenient and highly efficient method is described for the synthesis of -methoxycarbazole derivatives, including those with sterically demanding, benzannulated, or strongly electron-donating or -withdrawing substituents. Various -methoxycarbazole derivatives were directly prepared in good-to-moderate yields by the Pd (dba) CHCl /9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene-catalyzed reactions of the corresponding dibromobiphenyl compounds and methoxya-mine. Based on this methodology, the first total synthesis of 3,3′-[oxybis(methylene)]bis(9-methoxy-9 -carbazole), an antimicrobial dimeric carbazole alkaloid previously isolated from the stem bark of , was achieved in 18% yield over seven steps from 1,2-dibromobenzene.

Keywords： Ni>-methoxyl carbazole dimeric Ni>-methoxyl carbazole alkaloid total synthesis double Ni>-arylation of methoxyamine

HTML PDF Collect

Thermal and Mechanical Properties Optimization of ABi>O₄ Type EuNbO₄ By theBi>-Site Substitution of Ta Article

Lin Chen, Jing Feng

Engineering 2020, Volume 6, Issue 2, Pages 177-184 doi: 10.1016/j.eng.2019.12.006

Abstract:

Ferroelastic ABO₄ type RETaO₄ and RENbO₄ ceramics (where RE stands for rare earth) are being investigated as promising thermal barrier coatings (TBCs), and the mechanical properties of RETaO₄ have been found to be better than those of RENbO₄. In this work, B-site substitution of tantalum (Ta) is used to optimize the thermal and mechanical properties of EuNbO₄ fabricated through a solid-state reaction (SSR). The crystal structure is clarified by means of X-ray diffraction (XRD) and Raman spectroscopy; and the surface microstructure is surveyed via scanning electronic microscope (SEM). The Young's modulus and the thermal expansion coefficient (TEC) of EuNbO₄ are effectively increased; with respective maximum values of 169 GPa and 11.2×10^–6 K^–1 (at 1200 °C). The thermal conductivity is reduced to 1.52 W·K⁻¹·m⁻¹ (at 700 °C), and the thermal radiation resistance is improved. The relationship between the phonon thermal diffusivity and temperature was established in order to determine the intrinsic phonon thermal conductivity by eliminating the thermal radiation effects. The results indicate that the thermal and mechanical properties of EuNbO₄ can be effectually optimized via the B-site substitution of Ta, and that
this proposed material can be applied as a high-temperature structural ceramic in future.

Keywords： Thermal barrier coatings Rare earth niobates Substitution Thermal conductivity Thermal expansion coefficients Young’s modulus

HTML PDF Collect

Traces and echoes of De Architecturai> by Marcus Vitruvius Pollio in the work of Xu Guangqi in 17th

Michela CIGOLA,Yibing FANG

Frontiers of Mechanical Engineering 2016, Volume 11, Issue 1, Pages 3-11 doi: 10.1007/s11465-015-0359-5

Abstract: the 16th and 17th centuries by analyzing a book of Western technology that he wrote, namely, Taixi Shuifai> (On Western Hydraulicsi>).Taixi Shuifai>.found that Archimedes’ screw and Ctesibius’ machine, which are included in Vitruvius’ De Architecturai> volumes, also appear in the work of Xu Guangqi.

Keywords： Vitruvius’ De Architecturai> Xu Guangqi’s Taixi Shuifai> Jesuit missionaries Italian Renaissance

HTML PDF Collect

Accounting for the uncertainties in the estimation of average shear wave velocity using – correlations

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 5, Pages 1199-1208 doi: 10.1007/s11709-021-0749-1

Abstract: Shear wave velocity ( Vi> _S) is a key parameter in such analysis, although the economyVarious Vi> _S–SPT– Ni> correlations are routinely incorporated in seismic hazardanalysis to estimate the value of Vi> _S.i> _S calculations.The scattering nature of the Vi> _S values estimated using different Vi> _{S

Keywords：

uncertainties


Vi> _S– Ni> correlations


Vi> _S30


SPT data


statistical


HTML

PDF

Collect}

RR1i> and RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1, Pages 81-86 doi: 10.15302/J-FASE-2016088

Abstract: As virulence-determining genes, and encode the small subunit and large subunit of viral ribonucleotide reductase (RR) in pseudorabies virus which have been extensively studied in mice. However, their role in pigs has not been adequately investigated. In this study, we deleted and genes based on a / / triple gene-deleted pseudorabies virus and tested its efficacy in pigs as a vaccine candidate. The rescued virus showed similar growth properties and plaque size as its parent strain. In an animal study, the virus could elicit humoral immune responses shown by generation of gB-specific antibodies and virus neutralizing antibodies. However, vaccination could not provide protection against virulent pseudorabies virus challenge since vaccinated pigs showed clinical pseudorabies-specific syndromes. The deficiency in protection may due to the generation of late and low levels of gB antibodies and virus neutralizing antibodies.

Keywords： pseudorabies virus RR1i> and RR2i> ribonucleotide reductase vaccine candidate

HTML PDF Collect

Efficient acetoin production from pyruvate by engineered whole-cell biocatalysis

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 4, Pages 425-436 doi: 10.1007/s11705-022-2229-0

Abstract: Halomonas bluephagenesisi>, a chassis for next generation of industrial biotechnology, has advantagesHere, αi>-acetolactate synthase and αi>-acetolactate decarboxylase from Bacillus subtilisi> 168 were co-expressed in H. bluephagenesisi> to produce acetoin from pyruvate.After reaction condition optimization and further increase of αi>-acetolactate decarboxylase expressionThis work therefore provided an efficient H. bluephagenesisi> whole-cell catalysis with a broad

Keywords： acetoin pyruvate αi>-acetolactate synthetase αi>-acetolactate decarboxylase Halomonasbluephagenesisi> whole-cell biocatalysis

HTML PDF Collect

Title Author Date Type Operation

Catalytic oxidation of

Na Li, Xin Xing, Yonggang Sun, Jie Cheng, Gang Wang, Zhongshen Zhang, Zhengping Hao

Journal Article

Enhanced 4-chlorophenol biodegradation by integrating FeO nanoparticles into an anaerobic reactor: Long-term

Journal Article

The impact of hypoxia in hepatocellular carcinoma metastasis

Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Irene Oi-Lin Ng

Journal Article

Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

Sandy Leung-Kuen Au, Irene Oi-Lin Ng, Chun-Ming Wong

Journal Article

TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways in hepatocellular carcinoma

Daniel Wai-Hung Ho,Alan Ka-Lun Kai,Irene Oi-Lin Ng

Journal Article

Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

Journal Article

The Potential Role of Powdery Mildew-Resistance Gene Pm40i> in Chinese Wheat-Breeding Programs inthe Post-Pm21i> Era

Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo

Journal Article

NiFeRuO_xi> nanosheets on Ni foam as an electrocatalyst for efficient

Journal Article

Presence and Antimicrobial Susceptibility of RE-cmeABCi>-Positive Campylobacteri> Isolated

Dejun Liu, Weiwen Liu, Xing Li, Hong Yao, Zhangqi Shen, Yang Wang, Jianzhong Shen

Journal Article

A highly efficient methodology for the preparation of

Yongxin Zhang, Shucheng Wang, Yaodong Huang

Journal Article

Thermal and Mechanical Properties Optimization of ABi>O₄ Type EuNbO₄ By theBi>-Site Substitution of Ta

Lin Chen, Jing Feng

Journal Article

Traces and echoes of De Architecturai> by Marcus Vitruvius Pollio in the work of Xu Guangqi in 17th

Michela CIGOLA,Yibing FANG

Journal Article

Accounting for the uncertainties in the estimation of average shear wave velocity using – correlations

Journal Article

RR1i> and RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Journal Article

Efficient acetoin production from pyruvate by engineered whole-cell biocatalysis

Journal Article

京公网安备 11010502051620号京ICP备11030251号-2

关注我们